Adverse Effects: 
Cognitive- activation, excitement, impulse dycontrol, agitation, restlessness and insomnia, 
Increased dreaming, nightmares, 
Precipitation of hypomania or mania (in 3.7-20% of patients), pyschosis, panic reactions, anxiety, or euphoria may occur. 
Isolated reports of SSRI antidepressants causing agitation, motor activation, aggression, impulsivity, and suicidal urges. 
Apathy or amotivational syndrome reported. 

Precautions: 
May induce manic reactions in up to 20% of patients with bipolar affective disorder(BAD); because of risk of increased cycling, BAD is a relative contraindication. 

Pediatric Considerations: 
Children may be more prone to behavioral adverse effects including agitation, restlessness (32-46%), activation, hypomania (up to 13%), insomnia (up to 21%), irritability and social disinhibition (up to 25%). Increased risk of headache (21%).  Amotivational syndrome reported to emerge after several months of treatment (suggestive of frontal lobe dysfunction).  

Patient instructions: 
Do not stop these drugs suddenly as withdrawal reactions can occur. 
Avoid ingestion of grapefruit juice while taking fluvoxamine and sertraline, as the blood level of the antidepressant may rise. 
Rate of fluvoxamine absorption increased by ethanol. 
Cigarette smoking - Increased metabolism of fluvoxamine by 25% 
 

This info comes from: Clinical Handbook of Psychotropic Drugs, ed: Kalyna Z. Bezchlibnyk-Butler and J. Joel Jeffries, Hogrefe & Huber Publishers, Toronto, Canada, Ninth Edition 1999